Review of FlyBase

Title: FlyBase

URL: http://www.flybase.org/

Date Reviewed: May 25, 2004

Description:

The FlyBase is a database of genetic and molecular information for drosophila (the primary species is Drosophila melanogaster). The information in FlyBase includes:

°§         Information on genes and mutant alleles

°§         Information about the expression and properties of transcripts and proteins

°§         Information on the functions of gene products

°§         Nucleic acid accession numbers linked from gene records

°§         Protein sequence accession numbers linked from protein records

°§         Information about natural and engineered transposons and other molecular constructs

°§         Lists of genomic clones

°§         Descriptions of chromosomal aberrations

°§         Descriptions of Drosophila stocks held in stock centers and private labs

°§         Images that illustrate Drosophila anatomy and development terms

°§         A bibliography of Drosophila citations

°§         An address book of Drosophila researchers

°§         Drosophila genetic, cytological, and molecular map information

°§         Berkeley Drosophila Genome Project data

°§         European Drosophila Genome Project data

°§         Allied databases

°§         A searchable archive of bionet.drosophila postings

Strengths:

This website is a collaboration of Harvard University, University of Cambridge (UK), Indiana University, University of California, Berkeley, and the European Bioinformatics Institute, funded by NIH and MRC (UK).

The brief description for each gene is very understandable, and links to other useful information is convenient. The reference seems better than SGD. The allele link displays mutant constructs of a gene which might be loss-of-function, gain-of-fuction or dominant negative mutants, and their corresponding phenotypes. The update link displays recent information on certain gene.

Weaknesses:

Do not have a search engine for reference.

Comprehensiveness:

Very good.

Timeliness:

The website is updated every month.

Ease of Use:

Not bad. The summary part is good because it has a lot of hyperlinks.

Responsiveness:

Ok. Anyhow, it is faster than NCBI.

Similar or Related Sites:

SGD and MGI

Overall Evaluation:

4.5