Review of FlyBase

Title: FlyBase

URL: http://www.flybase.org/

Date Reviewed: May 25, 2004

Description:

The FlyBase is a database of genetic and molecular information for drosophila (the primary species is Drosophila melanogaster). The information in FlyBase includes:

         Information on genes and mutant alleles

         Information about the expression and properties of transcripts and proteins

         Information on the functions of gene products

         Nucleic acid accession numbers linked from gene records

         Protein sequence accession numbers linked from protein records

         Information about natural and engineered transposons and other molecular constructs

         Lists of genomic clones

         Descriptions of chromosomal aberrations

         Descriptions of Drosophila stocks held in stock centers and private labs

         Images that illustrate Drosophila anatomy and development terms

         A bibliography of Drosophila citations

         An address book of Drosophila researchers

         Drosophila genetic, cytological, and molecular map information

         Berkeley Drosophila Genome Project data

         European Drosophila Genome Project data

         Allied databases

         A searchable archive of bionet.drosophila postings

Strengths:

This website is a collaboration of Harvard University, University of Cambridge (UK), Indiana University, University of California, Berkeley, and the European Bioinformatics Institute, funded by NIH and MRC (UK).

The brief description for each gene is very understandable, and links to other useful information is convenient. The reference seems better than SGD. The allele link displays mutant constructs of a gene which might be loss-of-function, gain-of-fuction or dominant negative mutants, and their corresponding phenotypes. The update link displays recent information on certain gene.

Weaknesses:

Do not have a search engine for reference.

Comprehensiveness:

Very good.

Timeliness:

The website is updated every month.

Ease of Use:

Not bad. The summary part is good because it has a lot of hyperlinks.

Responsiveness:

Ok. Anyhow, it is faster than NCBI.

Similar or Related Sites:

SGD and MGI

Overall Evaluation:

4.5