Title: SYFPEITHI (Version 1.0)
URL: http://syfpeithi.bmi-heidelberg.com/
Date Reviewed:
Description: This is a database containing peptide
sequences known to bind Class I and Class II MHC molecules, compiled from
published reports.
Epitope Prediction: Uses an
algorithm to pick out possible peptide epitopes from
a given protein sequence in the context of a specified MHC.
Find Motif:
Identifies peptide motifs that are predicted to bind specified MHC molecules.
It lets you specify the source and length of peptide and anchor residues.
There’s also a provision to look among cancer-related ligands.
Strengths: Facilitates the search
for peptides and allows for the prediction of T-cell epitopes.
Some of these algorithms are in use but there are hardly any sites that run
them for you against a database of published information.
Weaknesses:
Comprehensiveness: Quite comprehensive – has a list of ~3500
peptide sequences and MHCs from human, mouse, chicken
and other species.
Timeliness: Good
Ease of Use: Good
Responsiveness: Good
Similar or
Related Sites:
Overall
Evaluation: I would give this site 4.5
stars
Reviewer: Srimoyee Ghosh
Email: srimoyee.ghosh@tufts.edu