Title: InterPro Home
URL:
http://www.ebi.ac.uk/interpro/
Date Reviewed:
Description: The site is maintained by
EBI. It combines a large number of bioinformatics tools under several broad
headings.
Homology and
Similarity: Has a number of search tools like NCBI and Wu BLAST, Fasta, Proteomes and Genomes Fasta
3 (which lets you search within a pretty comprehensive list of genomes as well
as some proteomes), Parasites Genome BLAST and so on.
Protein Functional
Analysis: Has InterProScan, protein fingerprint
searches (FingerPRINTScan), protein motif searches (ppsearch) as well as GeneQuiz.
Structural
Analysis: Several tools - programs like DALI for protein 3D structures comparisons,
Jrped for consensus secondary structure predictions,
PQS for quaternary structure, TOPS for protein structural topology among
others.
Sequence Analysis:
Tools like Clustal, Mutation Checker, Genetic Code
Viewer, TransSeq, Reverse
Translator etc.
Other than this,
there are miscellaneous tools like ReadSeq, tools for
expression array analysis, Protein Colourer which
lets you color code designated amino acids in a given protein.
Strengths: Very exhaustive allows a pretty holistic
analysis of a protein, provided one has the time to go through and use all the
tools.
Weaknesses: Not many although its
probably not as extensive as Expasy
Comprehensiveness: Good
Timeliness: Good the site was
recently updated (May 2002)
Ease of Use: Quite good there a short
descriptions against each program and the over-all
layout is quite easy to work with.
Responsiveness: Good most output
screens came up quite quickly. Some of the structural analysis programs (like
DALI) took relatively longer.
Similar or
Related Sites: http://www.expasy.ch/
Overall
Evaluation: I would give this site 4
stars
Reviewer: Srimoyee Ghosh
Email: srimoyee.ghosh@tufts.edu